Predicting outcomes of gastric peroral endoscopic myotomy using a gastric electrical mapping system: GPOEM-GEMS

Posted Tuesday April 16, 2024

This study is kindly funded by the NZSG Janssen Research Fellowship.


Gastroparesis is a chronic debilitating disorder with significant burden to patients and healthcare systems. GPOEM is an emerging treatment for medically refractory gastroparesis. However, a third of patients lack clinical benefit from the procedure at 1-year follow-up. Gastric Alimetry is a new test of gastric function using non-invasive electrical mapping and simultaneous symptom capture.


This international, multicentre, prospective, observational cohort study aims to determine if Gastric Alimetry can predict treatment response to GPOEM in patients with refractory gastroparesis. We aim to develop a clinical decision rule through a predictive model to enhance patient selection for GPOEM.


Patients being considered for GPOEM will undergo a Gastric Alimetry test within 30-days prior to their procedure, and subsequently be followed up at 1m, 3m, 6m, and 12m post-GPOEM using a patient-facing mobile app (MyCap).


If you would like to enrol to join the GPOEM-GEMS study, please email:

Dr Chris Varghese, University of

Image by: NZ Gastro Office



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